The service will operate up to seven times weekly from June until the end of October.
Ellie McGimpsey, Aviation Development Manager at Belfast City Airport, said: “We are thrilled that a connection between Faro and Belfast has once again been restored.
“We know there will be great demand from people from Northern Ireland to plan a getaway this summer in line with Government travel guidance. But this service really presents a great opportunity for people living in the Algarve with connections in Northern Ireland who may wish to travel home to see family.
“As a result of the pandemic, ex-pats living abroad have been separated from family and friends back home for over a year now so we hope this service will facilitate some very special reunions this summer.”